My advice steer clear of that run, did it yesterday but from Reading in the artic, it was a night trunk so i thought no problems 
not so :
M40 North Shut Junction 9, divert round Bicester 
M42 Road works + lane closure down to 1 lane 50 mph
M6 Road works + lane closures down to 1 / 2 lanes 40 / 50 mph
Coming back :
M6 Closed junction 16 due to bad crash divert A500 round Stoke On Trent
Back on to M6 at juction 15 lane closure due to Argos atric who went down the embankment, at which point i stopped filling sorry for myself and hoped the driver was ok and i thought there is always someone worst off.
Any it can’t be done unless road conditions are perfect, i.e no traffic 
no road works quick unload , ahh the perfect world, one day maybe