I don’t think that there is a ‘definitive’ answer. It would always depend upon the circumstances.
Someone came to me a year or so back somewhat ‘irked’ that running out of time, he had been directed to a ‘sister’ depot, which took him about 20 mins over his hours, rather than finding a lay by and dropping the trailer to be collected later.
I went through the scenario with him. He was loaded with foodstuffs. He didn’t have any means of securing the fridge doors. Could he guarantee finding a lay by where he could drop the trailer and then pull in behind it WITHOUT the risk of another vehicle reversing up to it and then ‘closing the curtains’?
What if he was carrying something like aerated bags of prepared salad, and a group of idiots had decided to get into the trailer and ■■■■ all over the load?
The end result may well have been undetectable, except by the end user. 
Or it was pork pies, and a spaced out needle user decided that it would be fun to prod a used needle into a number of the product?
Both scenarios are fanciful, as I’ll readily admit, but shouldn’t be ignored.
Following the conversation, the individual concerned was more ‘relaxed’ about the matter.
Thinking back to, rather than quoting from, the Regs, the safety of the public has primacy, which, I would suggest, but has never been decided upon, (AFAIK}, should/could include the driver, hence the ‘east end of Glasgow’ scenario. Following on from the safety of the vehicle, comes the ‘safety of the load’. (which obviously includes the ‘east end of Glasgow’ situation), where one may then have to consider matters such as Product Contamination and Public Health issues.
Whilst I’m not suggesting that there are vast numbers of terrorists, ‘eco’ or otherwise, out there waiting to pounce on any consumable load that we might render vulnerable, it only needs a few. 
And if the argument justifies getting to somewhere more disreable at which to rest, then why not use it. 