Happened to me once about 20 years ago . EC14 ERF 4x2 tractor unit with a 25000l unbaffled milk tanker on loaded with concentrate skim . Coming out of a town and putting the shoe down I must have been about 50 mph when the front drivers tyre on the unit went bang . Never touched the brakes as I was going up a slight hill just used the jake brake to bring myself to a stop. I was lucky in that it was the face of the tyre that went and not a sidewall - the 2 sidewalls came in and saved the rim . took 2 hours to get a new trye on and off I went . Wouldn’t want it happening again any time soon .