You do get used to it.
It’s a bit like when you’re on the ferry, you’re asleep whilst you have to get along with the engines running below you, with all the vibration and the general clanking noises that go along with them.
Depending on the time of year and what your carrying of course, you can choose the settings.
In winter, if it’s fresh at +2, I put it on stop/start, even if it’s frozen too. Very rare that it’ll go on while I’m asleep, but if it does it will only be for a short while whilst the fridge gets to the set temp.
As said it depends on what’s in the trailer, some goods have to be on constant.
We transport Ferrero chocolates set at +14, again on stop/start even in the summer. It will come on as needed.
We have drivers that prefer the fridge going all the time.