As said the closures have been higher up. I’d be more worried about the M11, A14, M1 closures. 48 to 49 was a one off whilst they reconfigured the lanes for a contraflow and you won’t be affected by 50-51 as you’ll have got off at either 44 to go up the A64/A169 or 49 to go up the A168/A19/A170 and take A169 from Pickering to Whitby.
If it says its shut anywhere between J36 and 41 as you approach the M18 take M18 northbound, M62 eastbound, off at J37 then take A614 to Driffield, nip up B1249 which will take you back on to the A64 near Scarborough and you can then go up to Whitby from there.